Research

The Lupus Alliance of LIQ is committed to supporting scientific and medical lupus research at local and national levels. One of Lupus Alliance of LIQ`s prime accomplishments has been to work collaboratively with the Lupus Research Institute (LRI) in its novel efforts to find better ways to treat and hopefully cure lupus. The Lupus Alliance of LIQ through your generous donations, has contributed over $550,000 to various research initiatives since 2002.

 

In the last few years, more funding has been directed at lupus research through government, for profit and non-profit organizations. For example, the National Institute of Health allocated $84 million in 2008 to fund lupus-related research. After so many years of under funding and unfocused attention in the research community, these initiatives are very encouraging.

 

There is a considerable amount of information on the web about lupus research. Keep coming back to our website to check out the latest information on research and related developments.

BIDMC Researchers Identify Enzyme that Contributes to Development of Lupus

BOSTON – Researchers at Beth Israel Deaconess Medical Center (BIDMC) have identified an enzyme that is significantly elevated in mouse models of systemic lupus erythematosus and in blood samples of patients with lupus. Published online today in The Journal of Clinical Investigation, the new findings demonstrate that inhibition of the SHP-2 enzyme can significantly diminish… Read More »

Study Reveals Role for Oxidized Mitochondrial DNA in Lupus

Researchers at the Baylor Institute for Immunology Research have discovered that the neutrophils of systemic lupus erythematosus (SLE) patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response. The study “Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus,” which will be published online April 18… Read More »

A Promising Future Treatment for Lupus

A promising future treatment for lupus – Innovate Long Island There’s a long tunnel ahead, but for millions around the world suffering from lupus, the light at the end shines brightly. That’s the fervent belief of Meggan Mackay, a board-certified rheumatologist and assistant professor at the Hofstra Northwell School of Medicine. Mackay is initiating a… Read More »

Chaos, Hope, and the Lupus Butterfly Theory

Lupus Butterfly Theory The lupus butterfly theory suggests that antibodies that attack DNA in lupus may be sources of both chaos and hope. In this image DNA-damaging antibodies are shown as purple butterflies, the symbol of lupus. Photo credit: Image by Christian Chang (www.christianchang.com) and James Hansen. Yale researchers believe some antibodies associated with lupus… Read More »

Understanding Molecular Diversity of Lupus Could Personalize Treatment Approach, Improve Clinical Trials

Understanding Molecular Diversity of Lupus Could Personalize Treatment Approach, Improve Clinical Trials – Lupus News Today In a landmark study, principal researcher Virginia Pascual at the Baylor Institute for Immunology Research, and colleagues, investigated the molecular diversity of lupus and found that a personalized immuno-monitoring approach allows for classification of patients into specific disease groups. Researchers believe these… Read More »

New Long-Term Organ Damage Analysis Published for GSK’s Benlysta®

GSK today announced publication of a new long-term analysis showing that patients with moderate-to-severe systemic lupus erythematosus (SLE) treated with Benlysta (belimumab) plus standard of care (SoC) over five years experienced low rates of organ damage progression, regardless of their baseline level of damage. Patients with SLE are at risk of irreversible organ damage which… Read More »

Lupus: Scientists Uncover Why Some Immune Cells Go Rogue

Systemic lupus erythematosus (SLE), is an enigmatic disease characterized by a hyperactive immune system that attacks normal cells, affecting various body systems such as joints, kidneys, blood cells, heart, lungs, and most noticeable to others, the skin—from which the disease is often first diagnosed due to the classic butterfly rash on the face. Researchers have… Read More »

New Tool Better Predicts Coronary Artery Disease in Lupus Patients

MAUI, HAWAII – Multiple studies have firmly established that the traditional Framingham Risk Score seriously underestimates the substantially increased risk of coronary artery disease present in patients with systemic lupus erythematosus (SLE). Nor is the American College of Cardiology/American Heart Association atherosclerotic cardiovascular disease risk score reliable in this population. But now physicians at the… Read More »